منابع مشابه
Long-term effectiveness of computer-generated tailored patient education on benzodiazepines: a randomized controlled trial.
AIMS Chronic benzodiazepine use is highly prevalent and is associated with a variety of negative health consequences. The present study examined the long-term effectiveness of a tailored patient education intervention on benzodiazepine use. DESIGN A randomized controlled trial was conducted comprising three arms, comparing (i) a single tailored intervention; (ii) a multiple tailored intervent...
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There exist a large number of drugs belonging to the benzodiazepine family. These include the 1,4-benzodiazepines such as diazepam, temazepam and oxazepam, the often more potent diazolo- and triazolo-groups represented by alprazolam, midazolam, triazolam etc. These drugs represent a large range of potencies from submilligram doses to over 100 mg and a range of polarities. Consequently, blood or...
متن کاملBenzodiazepines revisited.
zodiazepines’ and to develop some guidelines for the appropriate use of BZPs in clinical practice. The conclusion (too long to be cited in its entirety) contains a lot of interesting information. At that time, there were no data ‘to suggest that long-term therapeutic use of benzodiazepines by patients commonly leads to dose escalation or to recreational abuse’ [ 1 , p. 55] (in all fairness, thi...
متن کاملEffect of oral benzodiazepines on memory.
The effects of the oral administration of diazepam 5, 10 and 20 mg, flunitrazepam 0.5 and 1 mg and lorazepam 1, 2 and 4 mg on memory were studied in groups of healthy patients before surgery. The degree of sedation was noted also. A dose-related amnesic effect was produced by all the drugs, but this was not significant with diazepam 5 mg and lorazepam 1 mg. Larger doses of diazepam (10 and 20 m...
متن کاملCycloaddition of Diphenylnitrilimine to 1,5-Benzodiazepines
The cycloaddition reaction of diphenylnitrilimine on the 1,5-benzodiazepines has been studied. New molecules of triazolobenzodiazepines type have been isolated and characterized.
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ژورنال
عنوان ژورنال: BMJ
سال: 1984
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.288.6429.1534